Carotenoid isomerooxygenase

Carotenoid isomerooxygenase (EC 1.13.11.65, ninaB (gene)) is an enzyme with systematic name zeaxanthin:oxygen 15,15'-oxidoreductase (bond-cleaving, cis-isomerizing).[1] This enzyme catalyses the following chemical reaction

Carotenoid isomerooxygenase
Identifiers
EC no.1.13.11.65
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
zeaxanthin + O2 (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal

The enzyme from the moth Galleria mellonella and the fruit fly Drosophila melanogaster takes part in the synthesis of retinal .

References

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  1. ^ Oberhauser V, Voolstra O, Bangert A, von Lintig J, Vogt K (December 2008). "NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide". Proceedings of the National Academy of Sciences of the United States of America. 105 (48): 19000–5. Bibcode:2008PNAS..10519000O. doi:10.1073/pnas.0807805105. PMC 2596218. PMID 19020100.
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