The following individuals have served as the President of the College of Charleston since 1790. Prior to 1790, the college existed on paper only, despite the college's founding in 1770.
- Robert Smith (bishop), 1790–1797
- Thomas Bee Jr., 1798–1805
- George Buist, 1806–1808
- Elijah Dunham Rattoone, 1810
- Nathaniel Bowen, 1823–1824 and 1827–1828
- Jasper Adams, 1825–1826 and 1828–1836
- William Theophilus Brantley, 1838–1844
- William Peronneau Finley, 1845–1857
- Nathaniel Russell Middleton, 1857–1880
- Henry Elliott Shepherd, 1882–1897
- Harrison Randolph, 1897–1942
- George Daniel Grice, 1942–1966
- Walter Raleigh Coppedge, 1966–1968
- Theodore Stern, 1968–1978
- Edward McDaniel Collins Jr., 1978–1985
- Harry Lightsey Jr, 1986–1992
- Alex Sanders (politician), 1992–2001
- Leo Higdon, 2001–2006
- P. George Benson, 2007–2014
- Glenn F. McConnell, 2014–2018
- Andrew Hsu, 2019-
Pages in category "Presidents of the College of Charleston"
The following 9 pages are in this category, out of 9 total. This list may not reflect recent changes.