Cayo or cayó may refer to:
- Cayo (film), a 2005 Puerto Rican film starring Roselyn Sánchez
- Cayo District, a district in the west of the nation of Belize
- San Ignacio, Belize, a town in the Cayo District (originally named "El Cayo")
- Caio, Carmarthenshire, a village in Wales sometimes spelt with a 'y'
- Cayo Hundred, a geographic division named after the village
- "Cayó", a 2022 song by Arca
- Elsa Cayo (born 1951), Peruvian filmmaker
See also
edit- Caio (disambiguation)
- Cay (sand island)