Charles Cornwallis may refer to:
- Sir Charles Cornwallis (diplomat) (died 1629), English courtier and diplomat
- Charles Cornwallis, 2nd Baron Cornwallis (1632–1673), English landowner and politician
- Charles Cornwallis, 3rd Baron Cornwallis (1655–1698), British politician
- Charles Cornwallis, 4th Baron Cornwallis (1675–1721/22), British politician
- Charles Cornwallis, 1st Earl Cornwallis (1700–1762), British peer
- Charles Cornwallis, 1st Marquess Cornwallis (1738–1805), British Army officer and colonial administrator
- Charles Cornwallis, 2nd Marquess Cornwallis (1774–1823), British Tory politician