Charles Jacobs may refer to:
- Charles Fenno Jacobs (1904–1975), photojournalist, World War II and postwar period
- Charles Jacobs (Louisiana judge) (born 1970), state district court judge in Springhill, Louisiana
- Charles Jacobs (political activist), co-founder, president, and board member of the American Anti-Slavery Group
- Ron Jacobs (rugby union) (Charles Ronald Jacobs, 1928–2002), captain of the England national rugby union team
- Clare Jacobs (1886–1971), pole vault, 1908 Olympic Games, often mistakenly listed in sources as Charles Jacobs