Charles Moss may refer to:
- Charles Moss (bishop of Bath and Wells) (1711–1802), Anglican clergyman
- Charles Moss (bishop of Oxford) (1763–1811), Church of England bishop
- Charles Moss (cyclist) (1882–1963), English road racing cyclist
- Charles Moss (judge) (1840–1912), Canadian lawyer and judge
- Charles Edward Moss (died 1930), English-born South African botanist