Chládek (feminine Chládková) is a Czech surname derived from the Czech word chlád, meaning "coolness." Possibly a nickname for a reserved person. Notable people include:
- Dana Chladek, Czech-American kayaker
- Denisa Chládková, Czech tennis player
- František Chládek, Czech biathlete
- Marcel Chládek, Czech politician
- Patrícia Chládeková, Slovak footballer
- Zdeněk Chládek, Czech boxer