Chloral hydrate/magnesium sulfate/pentobarbital

Chloral hydrate/magnesium sulfate/pentobarbital
Combination of
Chloral hydrate	Sedative
Magnesium sulfate	Neuromuscular blocker
Pentobarbital	Barbiturate
Clinical data
Trade names	Equithesin
Identifiers
CAS Number	39373-60-9;

Chloral hydrate/magnesium sulfate/pentobarbital sodium, brand name Equithesin, is a combination anesthetic agent used as a general anesthetic in horses.^[1] It is administered intravenously to effect. For many years, it was the most commonly used injectable anesthetic in horses. Newer anesthetic agents such as injectable barbiturates, alpha-2 agonists, cyclohexylamines, and inhalants gradually replaced Equithesin. The drug has been off the market and unavailable for decades.^{[citation needed]}

This combination anesthetic agent contains 42.5 mg chloral hydrate, 21.2 mg magnesium sulfate and 8.86 mg pentobarbital per milliliter.^[2]

References

^ Studdert VP, Gay CC, Blood DC, eds. (2012). "Equithesin". Saunders comprehensive veterinary dictionary (4th ed.). Edinburgh: Elsevier Saunders. p. 393. ISBN 9780702047442.
^ Posner LP, Burns P (2009). "Chapter 11. Injectable anesthetic agents. Miscellaneous intravenous anesthetics". In Riviere JE, Papich MG (eds.). Veterinary pharmacology and therapeutics (9th ed.). Ames, Iowa: Wiley-Blackwell. pp. 291–292. ISBN 978-0-8138-2061-3.

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[1] Studdert VP, Gay CC, Blood DC, eds. (2012). "Equithesin". Saunders comprehensive veterinary dictionary (4th ed.). Edinburgh: Elsevier Saunders. p. 393. ISBN 9780702047442.

[2] Posner LP, Burns P (2009). "Chapter 11. Injectable anesthetic agents. Miscellaneous intravenous anesthetics". In Riviere JE, Papich MG (eds.). Veterinary pharmacology and therapeutics (9th ed.). Ames, Iowa: Wiley-Blackwell. pp. 291–292. ISBN 978-0-8138-2061-3.

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