Citatuzumab bogatox (VB6-845) is a monoclonal antibody Fab fragment fused with bouganin, a ribosome inactivating protein from the plant Bougainvillea spectabilis.[1] It has undergone preclinical development for the treatment of ovarian cancer and other solid tumors.[2]
Monoclonal antibody | |
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Type | Fab fragment |
Source | Humanized (from mouse) |
Target | TACSTD1 |
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Chemical and physical data | |
Formula | C3455H5371N921O1060S18 |
Molar mass | 77348.44 g·mol−1 |
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References
edit- ^ International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
- ^ Viventia Biotech Inc.: VB6-845 Archived 2010-03-29 at the Wayback Machine