Class 38 may refer to:
- German passenger locomotives with a 4-6-0 wheel arrangement operated by the Deutsche Reichsbahn comprising:
- Class 38.0: Bavarian P 3/5 N
- Class 38.2-3: Saxon XII H2
- Class 38.4: Bavarian P 3/5 H
- Class 38.5: JDŽ 109
- Class 38.10-40: Prussian P 8
- Class 38.41: BBÖ 209, JDŽ 03
- Class 38.42-44: ČSD Class 354.4
- Class 38.45-46: PKP Class Ok22
- Class 38.70: Baden IV e
- New South Wales Class 38 locomotive