Class 54 may refer to:
- A German goods train locomotive class with a 2-6-0 wheel arrangement operated by the Deutsche Reichsbahn which comprised the:
- Class 54.0: Prussian G 5.1
- Class 54.0II: BBÖ 60, PKP Class Ti12, PKP Class Ti16, JDŽ 131
- Class 54.1: BBÖ 260, PKP Class Ti11, ČSD Class 333.1
- Class 54.2-3: Prussian G 5.2
- Class 54.2-3II: BBÖ 360
- Class 54.4: BBÖ 460
- Class 54.5: ČSD Class 344.3
- Class 54.6: Prussian G 5.3
- Class 54.6II: PKP Class Ti1, PKP Class Ti3, JDŽ 128
- Class 54.7: PKP Class Ti2
- Class 54.8-12: Prussian G 5.4
- Class 54.10: Prussian G 5.5
- Class 54.12: Mecklenburg G 5.4
- Class 54.13: Bavarian C VI
- Class 54.14: Bavarian G 3/4 N
- Class 54.15-17: Bavarian G 3/4 H