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The cold-seep-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1]
| cold-seep-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of cold-seep-1 RNA | |
| Identifiers | |
| Symbol | cold-seep-1 |
| Rfam | RF03089 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
Cold-seep-1 motif RNAs are found in environmental DNA samples from a cold seep located in Norway. These metagenomic contigs are quite short, and it is consequently difficult to determine if the RNA motif might be larger than the one that was determined, and similarly difficult to determine which protein-coding genes might be associated with cold-seep-1 RNAs, if any. Therefore, it is ambiguous whether cold-seep-1 RNAs function as cis-regulatory elements or whether they operate in trans, and no hypothesis of the function of cold-seep-1 RNAs has been advanced.
References
edit- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.