Colegio San Ignacio may refer to
- Colegio San Ignacio de Loyola, a school in San Juan, Puerto Rico, founded in 1952.
- Colegio San Ignacio (Santiago de Chile), a school founded in 1856
- Colegio San Ignacio, Machalí
- Colegio San Ignacio, Medellín, Colombia
- Colegio San Ignacio, Caracas, Venezuela
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