College of the Sacred Heart may refer to:
- A former name of Regis University, Denver, Colorado
- A former name of Manhattanville College, Purchase, New York
- Baradene College of the Sacred Heart, Auckland, New Zealand
- Campion College of the Sacred Heart, former name of Campion High School (1880-1975), Prairie du Chien, Wisconsin
- Newton College of the Sacred Heart, Newton Centre, Massachusetts