In enzymology, a cortisol O-acetyltransferase (EC 2.3.1.27) is an enzyme that catalyzes the chemical reaction
| cortisol O-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.27 | ||||||||
| CAS no. | 9076-48-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- acetyl-CoA + cortisol CoA + cortisol 21-acetate
Thus, the two substrates of this enzyme are acetyl-CoA and cortisol, whereas its two products are CoA and cortisol 21-acetate.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:cortisol O-acetyltransferase. Other names in common use include cortisol acetyltransferase, corticosteroid acetyltransferase, and corticosteroid-21-O-acetyltransferase.
References
edit- Thomas PJ (October 1968). "Cortisol acetyltransferase from baboon brain". The Biochemical Journal. 109 (4): 695–6. doi:10.1042/bj1090695. PMC 1186958. PMID 4971640.
