In enzymology, a corydaline synthase (EC 2.1.1.147) is an enzyme that catalyzes the chemical reaction
corydaline synthase | |||||||||
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Identifiers | |||||||||
EC no. | 2.1.1.147 | ||||||||
CAS no. | 155807-67-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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- S-adenosyl-L-methionine + palmatine + 2 NADPH + H+ S-adenosyl-L-homocysteine + corydaline + 2 NADP+
The 4 substrates of this enzyme are S-adenosyl methionine, palmatine, NADPH, and H+, whereas its 3 products are S-adenosylhomocysteine, corydaline, and NADP+.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase.
References
edit- Rueffer M, Bauer W, Zenk MH (1994). "The formation of corydaline and related alkaloids in Corydalis cava in vivo and in vitro". Can. J. Chem. 72: 170–175. doi:10.1139/v94-026.