In molecular biology, the crustacean neurohormone family of proteins is a family of neuropeptides expressed by arthropods.[1] The family includes the following types of neurohormones:
- Crustacean hyperglycaemic hormone (CHH). CHH is primarily involved in blood sugar regulation, but also plays a role in the control of moulting and reproduction.
- Moult-inhibiting hormone (MIH). MIH inhibits Y-organs where moulting hormone (ecdysteroid) is secreted. A moulting cycle is initiated when MIH secretion diminishes or stops.
- Gonad-inhibiting hormone (GIH), also known as vitellogenesis-inhibiting hormone (VIH) because of its role in inhibiting vitellogenesis in female animals.
- Mandibular organ-inhibiting hormone (MOIH). MOIH represses the synthesis of methyl farnesoate, the precursor of insect juvenile hormone III in the mandibular organ.
- Ion transport peptide (ITP) from locust. ITP stimulates salt and water reabsorption and inhibits acid secretion in the ileum of the locust.
- Caenorhabditis elegans uncharacterised protein ZC168.2.
Crust_neurohorm | |||||||||
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Identifiers | |||||||||
Symbol | Crust_neurohorm | ||||||||
Pfam | PF01147 | ||||||||
InterPro | IPR001166 | ||||||||
PROSITE | PDOC00963 | ||||||||
SCOP2 | 1j0t / SCOPe / SUPFAM | ||||||||
OPM superfamily | 75 | ||||||||
OPM protein | 1j0t | ||||||||
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These neurohormones are peptides of 70 to 80 amino acid residues which are processed from larger precursors. They contain six conserved cysteines that are involved in disulfide bonds.
References
edit- ^ De Kleijn DP, Van Herp F (December 1995). "Molecular biology of neurohormone precursors in the eyestalk of Crustacea". Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 112 (4): 573–9. doi:10.1016/0305-0491(95)00126-3. PMID 8590372.