The CyVA-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] CyVA-1 motifs are found in Cyanobacteria, Acidobacteriota, and Verrucomicrobiota. Only one example of the RNA is known in any Acidobacterial organism, and only one CyVA-1 RNA was found in any Verrucomicrobial organism. This could suggest that the RNA is not well-established in these bacterial lineages, or simply reflect the fact that relatively few genome sequences are available for organisms in these phyla. CyVA-1 RNAs likely function in trans as sRNAs, and organisms commonly have 2 or 3 separate copies of the CyVA-1 RNA motif in their genomes.
| CyVA-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of CyVA-1 RNA | |
| Identifiers | |
| Symbol | CyVA-1 |
| Rfam | RF02965 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
References
edit- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.