Cyclone is a nickname for:
- Cy Young (1867-1955), American Hall-of-Fame baseball pitcher whose nickname "Cyclone" was shortened to "Cy"
- Cyclone Taylor (1884-1979), Canadian Hall-of-Fame hockey player
- Fabiano Aoki (born 1978), Brazilian kickboxer
- Cyclone Miller (1858-1916), American Major League Baseball pitcher
- Cyclone Ryan (1866-1917), Major League Baseball pitcher and first baseman for 12 games
- Cyclone Joe Williams (1886-1951), American baseball pitcher in the Negro leagues