In enzymology, a D-arabinitol 4-dehydrogenase (EC 1.1.1.11) is an enzyme that catalyzes the chemical reaction
| D-arabitol 4-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.11 | ||||||||
| CAS no. | 9028-18-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- D-arabinitol + NAD+ D-xylulose + NADH + H+
Thus, the two substrates of this enzyme are D-arabinitol and NAD+, whereas its 3 products are D-xylulose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-arabinitol:NAD+ 4-oxidoreductase. Other names in common use include D-arabitol dehydrogenase and arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.
References
edit- Characterization of Arabitol Dehyrogenase in Transplastomic Plants. LAP Lambert Academic Publishing. ISBN 978-3-659-49235-8
- Lin ECC (1961). "An inducible D-arabitol dehydrogenase from Aerobacter aerogenes". J. Biol. Chem. 236: 31–36. PMID 13762204.
- Wood WA, McDonough MJ, Jacobs LB (1961). "Ribitol and D-arabitol utilization by Aerobacter aerogenes". J. Biol. Chem. 236: 2190–2195.
