D-arabitol-phosphate dehydrogenase

D-arabitol-phosphate dehydrogenase (EC 1.1.1.301, APDH, D-arabitol 1-phosphate dehydrogenase, D-arabitol 5-phosphate dehydrogenase) is an enzyme with systematic name D-arabitol-phosphate:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

D-arabitol-phosphate dehydrogenase
Identifiers
EC no.1.1.1.301
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
D-arabitol 1-phosphate + NAD+ D-xylulose 5-phosphate + NADH + H+

This enzyme participates in arabitol catabolism. The enzyme also converts D-arabitol 5-phosphate to D-ribulose 5-phosphate at a lower rate.

References

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  1. ^ Povelainen M, Eneyskaya EV, Kulminskaya AA, Ivanen DR, Kalkkinen N, Neustroev KN, Miasnikov AN (April 2003). "Biochemical and genetic characterization of a novel enzyme of pentitol metabolism: D-arabitol-phosphate dehydrogenase". The Biochemical Journal. 371 (Pt 1): 191–7. doi:10.1042/BJ20021096. PMC 1223252. PMID 12467497.
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