D-glycero-alpha-D-manno-heptose-7-phosphate kinase (EC 2.7.1.168, D-alpha-D-heptose-7-phosphate kinase, hdda (gene)) is an enzyme with systematic name ATP:D-glycero-alpha-D-manno-heptose 7-phosphate 1-phosphotransferase.[1][2] This enzyme catalyses the following chemical reaction
| D-glycero-alpha-D-manno-heptose-7-phosphate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.1.168 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- D-glycero-alpha-D-manno-heptose 7-phosphate + ATP D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + ADP
The enzyme participates in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose.
References
edit- ^ Kneidinger B, Graninger M, Puchberger M, Kosma P, Messner P (June 2001). "Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose". The Journal of Biological Chemistry. 276 (24): 20935–44. doi:10.1074/jbc.m100378200. PMID 11279237.
- ^ Valvano MA, Messner P, Kosma P (July 2002). "Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides". Microbiology. 148 (Pt 7): 1979–89. doi:10.1099/00221287-148-7-1979. PMID 12101286.
External links
edit- D-glycero-alpha-D-manno-heptose-7-phosphate+kinase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
