D-glycero-alpha-D-manno-heptose-7-phosphate kinase

D-glycero-alpha-D-manno-heptose-7-phosphate kinase (EC 2.7.1.168, D-alpha-D-heptose-7-phosphate kinase, hdda (gene)) is an enzyme with systematic name ATP:D-glycero-alpha-D-manno-heptose 7-phosphate 1-phosphotransferase.[1][2] This enzyme catalyses the following chemical reaction

D-glycero-alpha-D-manno-heptose-7-phosphate kinase
Identifiers
EC no.2.7.1.168
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
D-glycero-alpha-D-manno-heptose 7-phosphate + ATP D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + ADP

The enzyme participates in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose.

References

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  1. ^ Kneidinger B, Graninger M, Puchberger M, Kosma P, Messner P (June 2001). "Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose". The Journal of Biological Chemistry. 276 (24): 20935–44. doi:10.1074/jbc.m100378200. PMID 11279237.
  2. ^ Valvano MA, Messner P, Kosma P (July 2002). "Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides". Microbiology. 148 (Pt 7): 1979–89. doi:10.1099/00221287-148-7-1979. PMID 12101286.
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