In enzymology, a D-ribulokinase (EC 2.7.1.47) is an enzyme that catalyzes the chemical reaction
| D-ribulokinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.1.47 | ||||||||
| CAS no. | 9026-40-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- ATP + D-ribulose ADP + D-ribulose 5-phosphate
Thus, the two substrates of this enzyme are ATP and D-ribulose, whereas its two products are ADP and D-ribulose 5-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-ribulose 5-phosphotransferase. This enzyme is also called D-ribulokinase (phosphorylating). This enzyme participates in pentose and glucuronate interconversions.
References
edit- FROMM HJ (1959). "D-Ribulokinase from Aerobacter aerogenes". J. Biol. Chem. 234 (12): 3097–101. doi:10.1016/S0021-9258(18)69628-0. PMID 13825363.
- Singh C, Glaab E, Linster C (2016). "Molecular Identification of D-Ribulokinase in Budding Yeast and Mammals". J. Biol. Chem. 292 (3): 1005–1028. doi:10.1074/jbc.M116.760744. PMC 5247636. PMID 27909055.
