In enzymology, a D-sorbitol dehydrogenase (acceptor) (EC 1.1.99.21) is an enzyme that catalyzes the chemical reaction
D-sorbitol dehydrogenase (acceptor) | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.99.21 | ||||||||
CAS no. | 9028-22-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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- D-sorbitol + acceptor L-sorbose + reduced acceptor
Thus, the two substrates of this enzyme are D-sorbitol and acceptor, whereas its two products are L-sorbose and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-sorbitol:acceptor 1-oxidoreductase. This enzyme is also called D-sorbitol:(acceptor) 1-oxidoreductase. This enzyme participates in fructose and mannose metabolism. It employs one cofactor, FAD.
References
edit- Shinagawa E, Ameyama M (1982). "Purification and characterization of D-sorbitol dehydrogenase from membrane of Gluconobacter suboxydans var-alpha". Agric. Biol. Chem. 46: 135–141. doi:10.1271/bbb1961.46.135.