Death-associated protein 1 is a protein that in humans is encoded by the DAP gene.[5][6][7]

DAP
Identifiers
AliasesDAP, death associated protein
External IDsOMIM: 600954; MGI: 1918190; HomoloGene: 3235; GeneCards: DAP; OMA:DAP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004394
NM_001291963

NM_146057

RefSeq (protein)

NP_001278892
NP_004385

NP_666169

Location (UCSC)Chr 5: 10.68 – 10.76 MbChr 15: 31.22 – 31.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DAP gene encodes a basic, proline-rich, 15-kD protein. Death-associated protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma.[7]

References

edit
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000112977Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039168Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Feinstein E, Druck T, Kastury K, Berissi H, Goodart SA, Overhauser J, Kimchi A, Huebner K (Feb 1996). "Assignment of DAP1 and DAPK--genes that positively mediate programmed cell death triggered by IFN-gamma--to chromosome regions 5p12.2 and 9q34.1, respectively". Genomics. 29 (1): 305–7. doi:10.1006/geno.1995.1255. PMID 8530096.
  6. ^ Deiss LP, Feinstein E, Berissi H, Cohen O, Kimchi A (Feb 1995). "Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death". Genes Dev. 9 (1): 15–30. doi:10.1101/gad.9.1.15. PMID 7828849.
  7. ^ a b "Entrez Gene: DAP death-associated protein".

Further reading

edit