Beta-defensin 127 is a protein that in humans is encoded by the DEFB127 gene.[3][4]

DEFB127
Identifiers
AliasesDEFB127, C20orf73, DEF-27, DEFB-27, DEFB27, bA530N10.2, hBD-27, defensin beta 127
External IDsHomoloGene: 89142; GeneCards: DEFB127; OMA:DEFB127 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_139074

n/a

RefSeq (protein)

NP_620713

n/a

Location (UCSC)Chr 20: 0.16 – 0.16 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.[4]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000088782Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB Jr (Feb 2002). "Discovery of five conserved beta -defensin gene clusters using a computational search strategy". Proc Natl Acad Sci U S A. 99 (4): 2129–33. Bibcode:2002PNAS...99.2129S. doi:10.1073/pnas.042692699. PMC 122330. PMID 11854508.
  4. ^ a b "Entrez Gene: DEFB127 defensin, beta 127".

Further reading

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