Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 is an enzyme that in humans is encoded by the DHX15 gene.[5][6]

DHX15
Identifiers
AliasesDHX15, DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p, DEAH-box helicase 15, hPrp43
External IDsOMIM: 603403; MGI: 1099786; HomoloGene: 1040; GeneCards: DHX15; OMA:DHX15 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001358

NM_001042620
NM_007839

RefSeq (protein)

NP_001349

NP_001036085
NP_031865

Location (UCSC)Chr 4: 24.52 – 24.58 MbChr 5: 52.31 – 52.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing.[6] It may have tumor suppressor activity.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000109606Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029169Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Imamura O, Sugawara M, Furuichi Y (Dec 1997). "Cloning and characterization of a putative human RNA helicase gene of the DEAH-box protein family". Biochem Biophys Res Commun. 240 (2): 335–40. doi:10.1006/bbrc.1997.7585. PMID 9388478.
  6. ^ a b "Entrez Gene: DHX15 DEAH (Asp-Glu-Ala-His) box polypeptide 15".
  7. ^ Ito S, Koso H, Sakamoto K (Oct 2017). "RNA helicase DHX15 acts as a tumour suppressor in glioma". Br J Cancer. 117 (9): 1349–1359. doi:10.1038/bjc.2017.273. PMC 5672939. PMID 28829764.

Further reading

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