DNAL4

Dynein light chain 4, axonemal is a protein that in humans is encoded by the DNAL4 gene.

DNAL4
Identifiers
Aliases	DNAL4, PIG27, MRMV3, dynein axonemal light chain 4
External IDs	OMIM: 610565; MGI: 1859217; HomoloGene: 38094; GeneCards: DNAL4; OMA:DNAL4 - orthologs
Gene location (Human) Chr. Chromosome 22 (human) Band 22q13.1 Start 38,778,508 bp End 38,794,198 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15 E1|15 37.85 cM Start 79,645,654 bp End 79,662,050 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis right uterine tube anterior pituitary oocyte cingulate gyrus anterior cingulate cortex right lobe of thyroid gland right frontal lobe amygdala Top expressed in spermatid zygote spermatocyte secondary oocyte dentate gyrus of hippocampal formation granule cell neural layer of retina entorhinal cortex seminiferous tubule ventricular zone right kidney More reference expression data BioGPS More reference expression data
Gene ontology Molecular function cytoskeletal motor activity protein binding microtubule motor activity cytoskeletal protein binding plus-end-directed microtubule motor activity dynein intermediate chain binding dynein light intermediate chain binding Cellular component cytoplasm plasma membrane cell projection cilium microtubule cytoskeleton dynein complex Biological process microtubule-based process microtubule-based movement Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10126 54152 Ensembl ENSG00000100246 ENSMUSG00000022420 UniProt O96015 Q9DCM4 RefSeq (mRNA) NM_005740 NM_017470 RefSeq (protein) NP_005731 NP_059498 Location (UCSC) Chr 22: 38.78 – 38.79 Mb Chr 15: 79.65 – 79.66 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Iwasaki M, Kuwata T, Yamazaki Y, Jenkins NA, Copeland NG, Osato M, Ito Y, Kroon E, Sauvageau G, Nakamura T (2005). "Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model". Blood. 105 (2): 784–793. doi:10.1182/blood-2004-04-1508. PMID 15454493.
• Collins JE, Goward ME, Cole CG, Smink LJ, Huckle EJ, Knowles S, Bye JM, Beare DM, Dunham I (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

External links

• DNAL4 human gene location in the UCSC Genome Browser.
• DNAL4 human gene details in the UCSC Genome Browser.