DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase (EC 2.1.1.236, RavNMT) is an enzyme with systematic name S-adenosyl-L-methionine:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N,N-dimethyltransferase.[1] This enzyme catalyses the following chemical reaction
| DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.236 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose
The enzyme is involved in the synthesis of dTDP-D-ravidosamine.
References
edit- ^ Kharel MK, Lian H, Rohr J (March 2011). "Characterization of the TDP-D-ravidosamine biosynthetic pathway: one-pot enzymatic synthesis of TDP-D-ravidosamine from thymidine-5-phosphate and glucose-1-phosphate". Organic & Biomolecular Chemistry. 9 (6): 1799–808. doi:10.1039/c0ob00854k. PMC 4482361. PMID 21264378.
External links
edit- DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose+N,N-dimethyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
