The DUF3085 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] DUF3085 motifs are found in one species in the genus Thauera, as well as various metagenomic sequences obtained from environmental DNA.
| DUF3085 | |
|---|---|
 Consensus secondary structure and sequence conservation of DUF3085 RNA | |
| Identifiers | |
| Symbol | DUF3085 |
| Rfam | RF02959 |
| Other data | |
| RNA type | Cis-reg |
| SO | SO:0005836 |
| PDB structures | PDBe |
DUF3085 motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. The genes they putatively regulate often encode the DUF3085 conserved protein domain or ParB, a protein often used by plasmids. However, because DUF3085 RNAs were not found in any fully sequenced organism, it was not possible to determine if DUF3085 RNAs are consistently located in plasmids.
References
edit- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.