Damasus can refer to:
- Pope Damasus I (330–384) or St. Damasus
- Pope Damasus II (died 1048)
- Damasus Scombrus, Greek orator from Tralles
- Damasus (beetle), a genus of leaf beetle in the subfamily Eumolpinae
- Damasus (canonist) (12th–13th centuries); see Bartholomew of Brescia
- Damasus (mythology), a soldier on the Trojan side in the Trojan War
- Damasus, king of Kourion on southern Cyprus in the 7th century BCE