Dapagliflozin/saxagliptin, sold under the brand name Qtern, is a fixed-dose combination anti-diabetic medication used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.[2][3] It is a combination of dapagliflozin and saxagliptin.[2][3] It is taken by mouth.[2][3]
| Combination of | |
|---|---|
| Dapagliflozin | SGLT-2 inhibitor |
| Saxagliptin | Dipeptidyl peptidase-4 inhibitor |
| Clinical data | |
| Trade names | Qtern |
| AHFS/Drugs.com | Professional Drug Facts |
| License data | |
| Pregnancy category |
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| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
The most common side effects include upper respiratory tract infection (such as nose and throat infections) and, when used with a sulphonylurea, hypoglycaemia (low blood glucose levels).[3]
Dapagliflozin/saxagliptin was approved for medical use in the European Union in July 2016, and in the United States in February 2017.[3][4]
Medical uses
editIn the United States, dapagliflozin/saxagliptin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.[2]
In the European Union, it is indicated in adults aged 18 years and older with type 2 diabetes:
References
edit- ^ "Dapagliflozin / saxagliptin (Qtern) Use During Pregnancy". Drugs.com. 28 June 2019. Archived from the original on 16 July 2020. Retrieved 14 July 2020.
- ^ a b c d e "Qtern- dapagliflozin and saxagliptin tablet, film coated". DailyMed. 24 January 2020. Archived from the original on 14 July 2020. Retrieved 14 July 2020.
- ^ a b c d e f g h "Qtern EPAR". European Medicines Agency (EMA). 17 September 2018. Archived from the original on 14 July 2020. Retrieved 14 July 2020. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
- ^ "Drug Approval Package: Qtern (dapagliflozin and saxagliptin)". U.S. Food and Drug Administration (FDA). 10 October 2018. Archived from the original on 14 July 2020. Retrieved 14 July 2020.
