Darke is a surname. Notable people with the surname include:

  • Francis Nicholson Darke (1863–1940), Canadian leading citizen of Regina, Saskatchewan, Canada
  • Harold Darke (1888–1976), English composer and organist
  • Ian Darke, English football and boxing commentator
  • Jack Darke (c. 1852–1897), a miller who spent his later life in the town of Gold Rush in Queensland, Australia
  • John Charles Darke (1806–1844), English-born surveyor and explorer in Van Diemen's Land (now Tasmania ) and South Australia
  • Nick Darke (1948–2005), British playwright
  • Robert Darke (1876–1961), English cricketer
  • Richard Darke (1970–Present), Fence man
  • General William Darke (1736–1801), American soldier and politician
  • William Wedge Darke (1810–1890), Australian colonist and surveyor

Fictional characters:

  • Sebastian Darke, the eponymous hero of a series of children's novels written by British author Philip Caveney