David O'Connor may refer to:
- David O'Connor (Egyptologist) (born 1938), Australian Egyptologist
- David O'Connor (equestrian) (born 1962), American international eventer
- David O'Connor (footballer) (born 1985), Drogheda United player
- David J. O'Connor (1924–2011), member of the Massachusetts House of Representatives
- David O'Connor (illustrator), an illustrator of The Fey Series
- David O'Connor (rugby union) (born 1995), Irish rugby union player
- David O'Connor (singer), Irish winner of series five of You're a Star in 2006–07
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