DeLeon or De Leon is a surname. Notable people with the surname include:
- Alexander DeLeon (born 1989), US musician
- Count de Leon (1788–1834), German alchemist and mystic, born Bernhard Müller
- Carlos De León (1959–2020), Puerto Rico-born US athlete in boxing
- Daniel De Leon (1856–1914), US political activist and newspaper editor
- Daryl DeLeon (born 2005), Filipino-British racing driver
- Edwin de Leon (1818–1891), US lawyer and newspaper editor
- Gloria DeLeon (born 1952), US social worker
- Idalis DeLeón (born 1966), US singer and television personality
- Jack DeLeon (1924–2006), US television actor
- José DeLeón (born 1960), Dominican Republic-born US athlete in baseball
- Kevin de León (born 1966), US politician
- Leroy DeLeon (born 1948), Trinidad & Tobago-born US athlete in football
- Luis DeLeón (born 1958), Puerto Rico-born US athlete in baseball
- Millie DeLeon (1873–1922), US stage performer
- Nick DeLeon (born 1990), US football player
- Oscar D'León (born 1943), Venezuelan musician
- Rafael de Leon (1908–1999), Trinidad & Tobago musician, known as Roaring Lion
- Ronnie Deleon (f. 1980s-1990s), US kickboxer
- Russ DeLeon (born 1965), US attorney and co-founder of PartyGaming
- Skylar Deleon (born 1979), US actor convicted of a 2004 murder
- Walter DeLeon (1884–1947), US screenwriter
This page lists people with the surname DeLeon.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.