Deborah Kay Morrison is an American cell biologist who is the chief of the Laboratory of Cell and Developmental Signaling at the National Cancer Institute. She conducts research characterizing the RAS pathway and the RAF family kinases and leads efforts to design new therapeutic strategies for cancer treatment.

Deborah K. Morrison
Alma materVanderbilt University School of Medicine
Scientific career
FieldsCell biology, cancer research, signal transduction
InstitutionsHarvard Medical School
University of California at San Francisco
National Cancer Institute

Education

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Morrison completed a Ph.D. from Vanderbilt University School of Medicine.[1] Her 1985 dissertation was titled Characterization of the virion-associated RNA polymerase of rabbit poxvirus using monoclonal antibodies.[2] She then began studying signal transduction as a postdoctoral fellow in the laboratories of Thomas M. Roberts at Harvard Medical School and Lewis T. Williams at the University of California, San Francisco.[1]

Career and Research

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Morrison joined the ABL-Basic Research Program in 1990 and became head of the Cellular Growth Mechanisms Section in 1995.[1][3] From 1996 to 1997, she was on sabbatical in the laboratory of Gerald M. Rubin at the University of California, Berkeley.[1]

Morrison joined the National Cancer Institute's (NCI) Center for Cancer Research in 1999 and became chief of the Laboratory of Cell and Developmental Signaling in 2006.[1] She is a leader in the study of the RAF kinases.[4] Her work has provided insights into the biochemical and structural basis of RAF activation and has guided the design of new therapeutic strategies.[4]

Awards and honors

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In 2013 and 2021, Morrison received the NIH Director's Award for her breakthroughs in cancer research. In 2022, Morrison was elected a member of the National Academy of Sciences.[1]

See also

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References

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  1. ^ a b c d e f "Staff directory". National Cancer Institute. Retrieved 2022-10-05.  This article incorporates text from this source, which is in the public domain.
  2. ^ Morrison, Deborah Kay (1985). Characterization of the virion-associated RNA polymerase of rabbit poxvirus using monoclonal antibodies (Ph.D. thesis). Vanderbilt University. OCLC 16800567.
  3. ^ "Principal Investigators". NIH Intramural Research Program. Retrieved 2022-10-06.  This article incorporates text from this source, which is in the public domain.
  4. ^ a b "The National Academy of Sciences". NIH Intramural Research Program. 2011-04-07. Retrieved 2022-10-06.  This article incorporates text from this source, which is in the public domain.
  This article incorporates public domain material from websites or documents of the National Institutes of Health.