A declaration of independence is an assertion of the independence of an aspiring state or states.
Declaration of Independence may also refer to:
- Declaration of Independence (Trumbull), 1817–18 painting by John Trumbull
- Declaration of Independence (film), 1938 American short drama film
- Declaration of Independence (EP), 2011 EP by alternative rock band No Americana
- Declaration of Independence (album), 2012 album by American country rap artist Colt Ford
- "The Declaration of Independence", a song by +/- from Self-Titled Long-Playing Debut Album, 2002