Dehydro-L-gulonate decarboxylase

The enzyme dehydro-L-gulonate decarboxylase (EC 4.1.1.34) catalyzes the chemical reaction

dehydro-L-gulonate decarboxylase
Identifiers
EC no.4.1.1.34
CAS no.9024-67-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins
3-dehydro-L-gulonate L-xylulose + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming). This enzyme participates in pentose and glucuronate interconversions.

References

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  • Smiley JD, Ashwell G (1961). "Purification and properties of beta-L-hydroxy acid dehydrogenase II. Isolation of beta-keto-L-gluconic acid, an intermediate in L-xylulose biosynthesis". J. Biol. Chem. 236: 357–364.