Delta Upsilon Fraternity House may refer to:
- Delta Upsilon Fraternity House (Champaign, Illinois), listed on the National Register of Historic Places in Champaign County, Illinois
- Delta Upsilon Chapter House (Ames, Iowa), listed on the National Register of Historic Places in Story County, Iowa
- Delta Upsilon Fraternity House (Ann Arbor, Michigan), listed on the National Register of Historic Places in Washtenaw County, Michigan