Dendroaspis natriuretic peptide (DNP) is a 38-residue peptide[1] and a member of natriuretic peptide family.[2] It is structurally similar to the atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) and possesses biologic properties similar to these natriuretic peptides.[2][1]
DNP was originally isolated from the venom of the green mamba snake (Dendroaspis angusticeps),[1] from which its name is derived.
References
edit- ^ a b c Schweitz, Hugues; Vigne, Paul; Moinier, Danielle; Frelin, Christian; Lazdunski, Michel (1992). "A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps)". The Journal of Biological Chemistry. 267 (20): 13928–13932. doi:10.1016/S0021-9258(19)49658-0. PMID 1352773.
- ^ a b Park, Seon-Ah; Kim, Tae-Geun; Han, Myung-Kwan; Ha, Ki-Chan; Kim, Sung-Zoo; Kwak, Yong-Geun (June 2012). "Dendroaspis natriuretic peptide regulates the cardiac L-type Ca 2+ channel activity by the phosphorylation of α 1c proteins". Experimental & Molecular Medicine. 44 (6): 363–368. doi:10.3858/emm.2012.44.6.041. ISSN 2092-6413. PMC 3389074. PMID 22366884.