In pathology, dermatopathic lymphadenopathy, is lymph node pathology due to skin disease.
Dermatopathic lymphadenopathy | |
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Other names | Dermatopathic lymphadenitis |
Micrograph showing dermatopathic lymphadenopathy with the characteristic paracortical histiocytosis and melanin-laden macrophages. H&E stain. | |
Specialty | Dermatology |
Cause
editAlso known as lipomelanotic reticulosis or Pautrier-Woringer disease, represents a rare form of benign lymphatic hyperplasia associated with most exfoliative or eczematoid inflammatory erythrodermas, including pemphigus, psoriasis, eczema, neurodermatitis, and atrophia senilis.
Diagnosis
editDermatopathic lymphadenopathy is diagnosed by a lymph node biopsy. It has a characteristic pattern of histomorphology and immunohistochemical staining:
- Paracortical histiocytosis
- Melanin-laden macrophages
- Eosinophils
- Plasma cells (medulla of lymph node)
Differential diagnosis
editTreatment
editThe treatment is based on the underlying cause.
See also
editReferences
editExternal links
edit- Dermatopathic lymphadenitis - pathconsultddx.com.