Deshaun or DeShaun is a masculine given name which may refer to:
- Deshaun Davis (born 1996), American football player
- Deshaun Fenwick (born 1999), American football player
- DeShaun Foster (born 1980), American former player
- Deshaun Thomas (born 1991), American basketball player
- Deshaun Watson (born 1995), American football player