Dessalines can refer to:
- Jean-Jacques Dessalines, a general and statesman of Haiti.
- La Dessalinienne, the national anthem of Haiti named in his honor.
- Arrondissement of Dessalines, a Haitian arrondissement in the Artibonite Department
- Dessalines, a town in the arrondissement of the same name
- Alcide Dessalines d'Orbigny, a French naturalist.