Diacylglycerol kinase (CTP dependent) (EC 2.7.1.174, DAG kinase, CTP-dependent diacylglycerol kinase, diglyceride kinase) is an enzyme with systematic name CTP:1,2-diacyl-sn-glycerol 3-phosphotransferase.[1][2] This enzyme catalyses the following chemical reaction
| Diacylglycerol kinase (CTP dependent) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.1.174 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- CTP + 1,2-diacyl-sn-glycerol CDP + 1,2-diacyl-sn-glycerol 3-phosphate
This enzyme requires Ca2+ or Mg2+ for activity.
See also
editReferences
edit- ^ Han GS, O'Hara L, Carman GM, Siniossoglou S (July 2008). "An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth". The Journal of Biological Chemistry. 283 (29): 20433–42. doi:10.1074/jbc.m802903200. PMC 2459266. PMID 18458075.
- ^ Han GS, O'Hara L, Siniossoglou S, Carman GM (July 2008). "Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase". The Journal of Biological Chemistry. 283 (29): 20443–53. doi:10.1074/jbc.m802866200. PMC 2459283. PMID 18458076.
External links
edit- Diacylglycerol+kinase+(CTP+dependent) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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