Diapolycopene oxygenase (EC 1.14.99.44, crtP) is an enzyme with systematic name 4,4'-diapolycopene,AH2:oxygen oxidoreductase (4,4'-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction
| Diapolycopene oxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.99.44 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 4,4'-diapolycopene + 4 AH2 + 4 O2 4,4'-diapolycopenedial + 4 A + 6 H2O
Diapolycopene oxygenase is involved in the biosynthesis of C30 carotenoids such as staphyloxanthin.
References
edit- ^ Mijts BN, Lee PC, Schmidt-Dannert C (April 2005). "Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution". Chemistry & Biology. 12 (4): 453–60. doi:10.1016/j.chembiol.2005.02.010. PMID 15850982.
- ^ Tao L, Schenzle A, Odom JM, Cheng Q (June 2005). "Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde". Applied and Environmental Microbiology. 71 (6): 3294–301. doi:10.1128/AEM.71.6.3294-3301.2005. PMC 1151855. PMID 15933032.
External links
edit- Diapolycopene+oxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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