Diapolycopene oxygenase

Diapolycopene oxygenase (EC 1.14.99.44, crtP) is an enzyme with systematic name 4,4'-diapolycopene,AH2:oxygen oxidoreductase (4,4'-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction

Diapolycopene oxygenase
Identifiers
EC no.1.14.99.44
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
4,4'-diapolycopene + 4 AH2 + 4 O2 4,4'-diapolycopenedial + 4 A + 6 H2O

Diapolycopene oxygenase is involved in the biosynthesis of C30 carotenoids such as staphyloxanthin.

References

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  1. ^ Mijts BN, Lee PC, Schmidt-Dannert C (April 2005). "Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution". Chemistry & Biology. 12 (4): 453–60. doi:10.1016/j.chembiol.2005.02.010. PMID 15850982.
  2. ^ Tao L, Schenzle A, Odom JM, Cheng Q (June 2005). "Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde". Applied and Environmental Microbiology. 71 (6): 3294–301. doi:10.1128/AEM.71.6.3294-3301.2005. PMC 1151855. PMID 15933032.
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