Diethylstilbestrol dilaurate (brand name Acnestrol-Lotion) is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was previously marketed but is now no longer available.[1][2] It was formulated and used as a micronized topical medication to treat acne in adolescent boys and young men.[2][3] The drug was marketed as early as 1951.[4]
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Trade names | Acnestrol-Lotion |
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CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C42H64O4 |
Molar mass | 632.970 g·mol−1 |
3D model (JSmol) | |
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References
edit- ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 397. ISBN 978-1-4757-2085-3.
- ^ a b Canadian Pharmaceutical Association (1963). Compendium of pharmaceutical specialties (Canada) 1963. Canadian Pharmaceutical Association. p. 14.
- ^ Frank SB (1971). Acne Vulgaris. Thomas. p. 259. ISBN 9780398006020.
- ^ New York State Journal of Medicine. Medical Society of the State of New York. April 1951. p. 1313.