Dimethylcarbamoyl fluoride

Dimethylcarbamoyl fluoride
Names
	Preferred IUPAC name Dimethylcarbamoyl fluoride
Identifiers
CAS Number	431-14-1;
3D model (JSmol)	Interactive image;
ChemSpider	9507;
PubChem CID	9891;
CompTox Dashboard (EPA)	DTXSID20195689 ;
	InChI InChI=1S/C3H6FNO/c1-5(2)3(4)6/h1-2H3 Key: IRSDGYFTDVBVAK-UHFFFAOYSA-N;
	SMILES CN(C)C(=O)F;
Properties
Chemical formula	C3H6FNO
Molar mass	91.085 g·mol−1
Appearance	Colorless liquid
Solubility in water	Soluble
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Highly toxic
Related compounds
Related compounds	Dimethylcarbamoyl chloride
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Dimethylcarbamoyl fluoride is a chemical compound that can be produced by fluorination of dimethylcarbamoyl chloride with potassium fluoride.^[1] It is a colorless liquid that is soluble and stable in water.^[2]^[3]

Dimethylcarbamoyl fluoride is a potent cholinesterase inhibitor and is lethal even at low doses.^[2]^[3]

References

^ Cuomo, John; Olofson, R. A. (March 1979). "Efficient and convenient synthesis of fluoroformates and carbamoyl fluorides". The Journal of Organic Chemistry. 44 (6): 1016–1017. doi:10.1021/jo01320a034.
^ ^a ^b Augustinsson, K.B.; Casida, J.E. (December 1959). "Enzymic hydrolysis of N:N-dimethylcarbamoyl fluoride". Biochemical Pharmacology. 3 (1): 60–67. doi:10.1016/0006-2952(59)90009-7. PMID 13795122.
^ ^a ^b MYERS, DK (April 1956). "Studies on cholinesterase. 10. Return of cholinesterase activity in the rat after inhibition by carbamoyl fluorides". The Biochemical Journal. 62 (4): 556–63. doi:10.1042/bj0620556. PMC 1215962. PMID 13315214.

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