Dinovernavirus is a genus of double-stranded RNA viruses in the family Reoviridae and subfamily Spinareovirinae. Member viruses replicate in a variety of mosquito cell lines. The name is an abbreviation for double-stranded, insect, novem (Latin for nine the number of genome segments), rna virus. There is one species in the genus: Aedes pseudoscutellaris reovirus.[1][2]
| Dinovernavirus | |
|---|---|
| |
| Cryo-EM reconstruction of Fako virus capsid showing: turret protein (red), clamp protein (yellow), and homodimer of major capsid protein (blue/purple) | |
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Duplornaviricota |
| Class: | Resentoviricetes |
| Order: | Reovirales |
| Family: | Sedoreoviridae |
| Subfamily: | Spinareovirinae |
| Genus: | Dinovernavirus |
Structure
editViruses in Dinovernavirus are non-enveloped. Their capsid is turreted and single shelled with icosahedral geometries and T=2 symmetry. The diameter is around 49–50 nm.[1]
Genome
editGenomes are linear and segmented. There are nine segments which code for nine proteins.[1]
Life cycle
editViral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus transcription is the method of transcription. The virus exits the host cell by monopartite non-tubule guided viral movement. Mosquito serve as the natural host.[1]
Taxonomy
editThere is one species in the genus:[2]
- Aedes pseudoscutellaris reovirus
References
edit- ^ a b c d "Viral Zone". ExPASy. Retrieved 13 August 2015.
- ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 13 May 2021.