In enzymology, a dolichol O-acyltransferase (EC 2.3.1.123) is an enzyme that catalyzes the chemical reaction
| dolichol O-acyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.123 | ||||||||
| CAS no. | 111839-04-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- palmitoyl-CoA + dolichol CoA + dolichyl palmitate
Thus, the two substrates of this enzyme are palmitoyl-CoA and dolichol, whereas its two products are CoA and dolichyl palmitate.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:dolichol O-palmitoyltransferase. This enzyme is also called acyl-CoA:dolichol acyltransferase.
References
edit- Tollbom O, Valtersson C, Chojnacki T, Dallner G (1988). "Esterification of dolichol in rat liver". J. Biol. Chem. 263 (3): 1347–52. PMID 3121628.
