The domino effect is a type of chain reaction.
Domino Effect may also refer to:
- The domino theory, a political theory about the spread of communism
- Domino Effect (The Blizzards album), 2008
- Domino Effect (Gotthard album), 2007
- "Domino Effect" (Addictive song), 2009
- "Domino Effect", a song by Ozma, from their album Rock and Roll Part Three
- The Domino Effect (novel), a 2003 Doctor Who novel
- "The Domino Effect" (Amphibia), an episode of Amphibia
- "The Domino Effect", an episode of Sex and the City
- The Domino Effect (concert), a 2009 tribute concert to Fats Domino
- The Domino Effect, an album by Zerra One
- Domino Effect (TV series), a Polish documentary series, 2014